Implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.
| Version: | 1.1.0 |
| Depends: | R (≥ 3.6.0) |
| Imports: | Rcpp (≥ 1.0.4), scatterplot3d, stats, graphics, grDevices |
| LinkingTo: | Rcpp |
| Suggests: | rgl, igraph, knitr, rmarkdown, testthat |
| Published: | 2021-01-05 |
| Author: | Phillip B. Nicol |
| Maintainer: | Phillip B. Nicol <philnicol740 at gmail.com> |
| BugReports: | https://github.com/phillipnicol/SITH/issues |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| URL: | https://github.com/phillipnicol/SITH |
| NeedsCompilation: | yes |
| Materials: | NEWS |
| CRAN checks: | SITH results |
| Reference manual: | SITH.pdf |
| Vignettes: |
Simulating spatial tumor growth with SITH |
| Package source: | SITH_1.1.0.tar.gz |
| Windows binaries: | r-devel: SITH_1.1.0.zip, r-release: SITH_1.1.0.zip, r-oldrel: SITH_1.1.0.zip |
| macOS binaries: | r-release (arm64): SITH_1.1.0.tgz, r-oldrel (arm64): SITH_1.1.0.tgz, r-release (x86_64): SITH_1.1.0.tgz, r-oldrel (x86_64): SITH_1.1.0.tgz |
| Old sources: | SITH archive |
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