factorial2x2: Design and Analysis of a 2x2 Factorial Trial

Used for the design and analysis of a 2x2 factorial trial for a time-to-event endpoint. It performs power calculations and significance testing as well as providing estimates of the relevant hazard ratios and the corresponding 95% confidence intervals. Important reference papers include Slud EV. (1994) <https://www.ncbi.nlm.nih.gov/pubmed/8086609> Lin DY, Gong J, Gallo P, Bunn PH, Couper D. (2016) <doi:10.1111/biom.12507> Leifer ES, Troendle JF, Kolecki A, Follmann DA. (2020) <https://github.com/EricSLeifer/factorial2x2/blob/master/Leifer%20et%20al.%20paper.pdf>.

Version: 0.2.0
Depends: R (≥ 3.6.0), survival, stats, mvtnorm
Suggests: knitr, rmarkdown
Published: 2020-04-27
Author: Eric Leifer and James Troendle
Maintainer: Eric Leifer <Eric.Leifer at gmail.com>
License: GPL-2
NeedsCompilation: no
Materials: README NEWS
CRAN checks: factorial2x2 results

Documentation:

Reference manual: factorial2x2.pdf
Vignettes: factorial2x2

Downloads:

Package source: factorial2x2_0.2.0.tar.gz
Windows binaries: r-devel: factorial2x2_0.2.0.zip, r-release: factorial2x2_0.2.0.zip, r-oldrel: factorial2x2_0.2.0.zip
macOS binaries: r-release (arm64): factorial2x2_0.2.0.tgz, r-oldrel (arm64): factorial2x2_0.2.0.tgz, r-release (x86_64): factorial2x2_0.2.0.tgz, r-oldrel (x86_64): factorial2x2_0.2.0.tgz
Old sources: factorial2x2 archive

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