plinkQC 0.3.4
major changes
- Add flag for removing high LD regions and add option for user provided file, allowing removal of high LD regions for non-human organisms; fix missing flag 19bc569 and #42
- Fixed failing data.no_failIDs.lmiss file in check_snp_missingness function when failIDs were present 86adc39 and #43
plinkQC 0.3.3
major changes
- Output all IBD estimates in
run_check_relatedness
not just fail IBD estimates d009da90
- Add midp modifier for –hwe and –hardy as recommended on plink hwe documentation and discussed in issue #27; 43230a6c
- Provide HapMap and 1000Genomes individual and population identifiers as default for ancestry check functions; include optional color mapping for these reference populations; raised in #37, incorporated in 65cfcba
- for all individual QC functions return data.frame with FID, IID and measure used for filtering #5 incorporated in 295505b
- allow for user-supplied individual and marker filtering in perIndividualQC, perMarkerQC and cleanData #33
- individual highlighting in perIndividualQC plots; several highlight modalities (text/label, shape, color) #38
minor changes
- Add checks in
cleanData
that can distinguish between miss-specified filters and non-failing samples 7432b1ee; addresses issue #31
- Add checks and tests in
check_snp_missingness
, check_maf
and check_hwe
in cases where all samples pass perIndividualQC
. 31ed6f65; related to issue #31
- Add checks and tests in
evaluate_check_sex
and evaluate_check_het_imiss
for all passing samples and accordingly, no fail samples label in plot. d071a43
- Update dropbox links and add note to vignette 9bae988
- additional plotting parameters for
evaluate_*
functions, controlling text and title sizes (b38a348, f25b8d0)
plinkQC 0.3.2
minor changes
- Add checks and tests in
evaluate_check_ancestry
for missing non-reference samples 5c03971
- Clarified tutorials:
- R internal file.copy instead of systems
cp
command to make run on windows: 6c91ef3, fixes #26
- Add additional filter for A->T, C->G variants as suggested in #24; 11e0375
- Fixed plotting issues in PCA plot of ancestry check:
- allow for supplying names of European reference population ae09e64
- provide argument to specify number of populations per legend row c7fe85d
- Ensure correct ordering of population colors when reference population is not HapMap 86275b7
plinkQC 0.3.1
minor changes
- Fixed dead links in vignettes (caused by migration of repository): da987d8
- Added note about chrY in Hapmap data (vignette): e8afbb9
- Added note about recommended use of plink1.9 (vs 2.0): b69d3d7
plinkQC 0.3.0
major changes
- Relationship filter can handle more complicated relationship scenarios as observed in plant genotype sets (fixed #11)
- code moved to the meyer-lab repository: https://github.com/meyer-lab-cshl/plinkQC
plinkQC 0.2.3
major changes
- Enable return of overview plots as ggplot object (fixes #6 in ab2e840 and 101e74e)
- Relationship filter now deals with more complicated relationship scenarios as observed in plant genotype sets (addresses #11)
minor changes
- give user option to choose maf threshold for relatedness filtering (relates to #3)
bug fixes
- Include check for zero related individuals fixing #3 in 1445a88
- Include check in case all samples fail perIndividual QC in 894acc1 and 0464224)
- Include checks for diagonal derived relationship estimates, and estimate data containing only related individuals; addresses #11
- Fix command for genotype conversion in 1000Genomes vignette, addressing issue #10
- fix missing rownames error for overviewPerIndividualQC, when relatedness check was included (issue #16, fc7a38b)
- fix vignette mismatch (issue #16, 09dcd59)
plinkQC 0.2.2
minor changes
- Fix IDs written to fail.IDs file: previous versions wrote IID,IID, now fixed to FID, IID (fixes #2).
plinkQC 0.2.1
minor changes
- Fix path check bug in checkPlink
- Include test data in build!
plinkQC 0.2.0
major changes
- All system calls to plink are conducted with sys::exec_wait - this should solve platform dependent issues, mainly compatibility with windows.
- Make path construction compatible with windows.
- path2plink now requires full path to plink executable, no tilde expansion or simple pointer to directory supported.
- Fix bug in return of cleanData function: list now contains keep and fail IDs.
- Fix bug in return of maf computation: if fail.IDs does not exist, set fail_samples to zero.
minor changes
- IBD-fail.IDs now saved without column names to be consistent with other xxx-fail.IDs files.
- Include additional progress messages in cleanData()
- Remove default double-specification of mafTh and macTh
- use checkPlink to return correct path2plink and export to make checkPlink directly accesible to user.
plinkQC 0.1.1
major changes
- run_check_relatedness will only save IBD estimates of individuals whose estimates are higher than the threshold.
minor changes
- Fix examples in vignettes 1000 Genomes and HapMap III reference.
- Change file access in function examples
- Add additional checks in check_ancestry and fix missing refSamplesFile test
plinkQC 0.1.0
- Added a
NEWS.md
file to track changes to the package.