The goal of vanquish is to detect whether a sample with variant information is contaminated by another sample from the same species.
This is a basic example which shows you how to detect whether vcf_example is contaminated:
## basic example code
library('vanquish')
data(vcf_example)
result <- defcon(file = vcf_example)
print(result$stat)
#> Name LOH HomVar HetVar HomRate HighRate
#> 1 sssc_test.vcf.gz 0.7248322 0.0001565125 0.02757586 0.536965 0.05350195
#> HetRate LowRate AvgLL
#> 1 0.3608949 0.04669261 -2.01978
print(result$result)
#> Name Class Regression
#> 1 sssc_test.vcf.gz 1 0.7131992Given class = 1, vcf_example is considered to be contaminated.